Daily Archives: November 3, 2013

What is Ergothioneine?

Ergothioneine is an antioxidant amino acid that occurs naturally in the body and is found in high concentrations around cells that are subjected to free radical damage. However, we can’t synthesize it, so we need to obtain it from our diet. Please don’t tell me it can only be found in broccoli or brussel sprouts. […]

Ergothioneine is a natural skin antioxidant

EGT is a natural skin antioxidant, as evidenced by the presence of the EGT transporter in fibroblasts. EGT is a more powerful antioxidant than either coenzyme Q(10) or idebenone due to its relatively greater efficiency in directly scavenging free radicals and in protecting cells from UV-induced ROS via A comparison of the relative antioxidant p… […]

Ergothioneine & Oxidative and DNA Damage

Ergothioneine protects the skin from oxidative and DNA damage. It is an antioxidant, protecting the mitochondrial membrane against oxidation. It will transfer fatty acids into the mitochondria to help use oxygen efficiently and to produce more energy. It also protects DNA from the oxidation of guanine. Ergothioneine reduces TNF-Alpha (Tumor Necrosis Factor), a stress signal […]

L-Ergothioneine & Skincare

Ergothioneine or l-ergothioneine is an ingredient that has become more common in skin care formulations over the last decade. Research about the benefits of the substance is still underway, and scientists\’ opinions about the effectiveness of the ingredient currently conflict. Still, many people who use products that feature l-ergothioneine as an active ingredient report receiving […]

Skin cells and tissue are capable of using l-ergothioneine as an integral component of their antioxidant defense system

The cellular defense system against harmful levels of reactive oxygen species consists of antioxidant enzymatic activities and small nonenzymatic molecules. l-Ergothioneine has long been recognized as a potent and stable low-molecular-weight antioxidant that humans consume with diet and that accumulates in cells normally subjected to high levels of oxidative stress. As l-ergothioneine is plasma membrane-impermeative, […]