Category hepcidin

Vitamin D is a potent suppressor of hepcidin in humans

\”For the first time, we have shown results, both in vitro and in vivo, indicating that vitamin D is a potent suppressor of hepcidin in humans. We propose that these findings provide a clinically relevant mechanism showing how vitamin D supplementation can improve anemia management in CKD patients,\” Dr. Bacchetta explained. via Vitamin D Lowers Hepcidin Levels in CKD […]

Vitamin D Lowers Hepcidin Levels in CKD Patients

Vitamin D supplementation is safe and economic for patients with chronic kidney disease (CKD); it can also decrease the need for erythropoietin-stimulating agents and ward off anemia by decreasing hepcidin levels and increasing ferroportin levels. A new study has confirmed the positive effects of vitamin D on hepcidin and ferroportin levels in the serum of patients with […]

A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats

Background Anemia is a common complication of chronic kidney disease (CKD) that negatively impacts the quality of life and is associated with numerous adverse outcomes. Excess levels of the iron regulatory hormone hepcidin are thought to contribute to anemia in CKD patients by decreasing iron availability from the diet and from body stores. Adenine treatment […]