Daily Archives: May 5, 2014

Ergothioneine: A New Vitamin? | NutritionFacts.org

Ergothioneine was discovered a century ago but ignored until recently when researchers found that we have a transporter protein in our bodies specifically designed to pull it out of our diets and into our tissues. This suggests that it plays some important physiological role, but what does it do? Well our first clue was the […]

Ergothioneine – Wikipedia

Ergothioneine is a naturally occurring amino acid and is a thiourea derivative of histidine, containing a sulfur atom in the imidazole ring. This compound is made in rather few organisms, notably Actinobacteria and filamentous fungi.[1] Ergothioneine was discovered in 1909 and named after the ergot fungus from which it was first purified, with its structure […]

L-Ergothioneine Protects Skin Cells against UV-Induced Damage—A Preliminary Study

Many changes related to aging at the cellular level may be due to the physiological condition of mitochondria. One of the most common types of damage of mtDNA is the so-called “common deletion” referring to a deletion of 4977 base pairs. In the skin cells this phenomenon probably is caused by oxidative damage of mtDNA […]

Ergothioneinein Mushrooms-Nature’s Best Source of a New Human Vitamin?

Robert Beelman – Professor of Food Science, Penn State University History L-ergothioneine (ERGO) is a naturally occurring dietary antioxidant whose name is derived but the fact that it was first identified in the sclerotia of the ergot fungus (Tauret, 1909) •Ergo is not synthesized by higher plants or animals but is taken up from the […]

The unusual amino acid L-ergothioneine is … [Cell Death Differ. 2010] – PubMed – NCBI

Ergothioneine (ET) is an unusual sulfur-containing derivative of the amino acid, histidine, which is derived exclusively through the diet. Although ET was isolated a century ago, its physiologic function has not been clearly established. Recently, a highly specific transporter for ET (ETT) was identified in mammalian tissues, which explains abundant tissue levels of ET and […]